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TFG Mouse anti-Human, Clone: OTI2C3, lyophilized, TrueMAB™
SDP

Catalog No. 501662434
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100 μg
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50-166-2434 100 μg
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Catalog No. 50-166-2434 Supplier OriGene Supplier No. CF503858
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Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TFG protein, a recently identified novel protein, is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region followed by octicosapeptide repeats. Research shows that TFG can modulate SHP-1 activity and is a novel member of the NF-kB pathway. The physiological functions of this protein remain largely elusive, but TFG is thought to function by associating with other proteins, including TANK and NEMO. TFG was first identified as a partner of NTRK1 and is involved in generating the thyroid TRK-T3 oncogene, as well as oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.

Specifications

Antigen TFG
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2C3
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene TFG
Gene Accession No. Q92734
Gene Alias HMSNP, SPG57, TF6, TRKT3
Gene Symbols TFG
Host Species Mouse
Immunogen Full length human recombit protein of human TFG produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10342
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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