Invitrogen™ TFIP11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597175

Catalog No. PIPA597175

Description

Immunogen sequence: MSLSHLYRDG EGRIDDDDDE RENFEITDWD LQNEFNPNRQ RHWQTKEEAT YGVWAERDSD DERPSFGGKR ARDYSAPVNF ISAGLKKGAA EEAELEDSDD EEKPVKQDDF PKDFGPRKLK TGGNFKPSQK GFAGGTKSFM; Positive Samples: LO2, HeLa, A-431, MCF-7, HT-1080, Mouse brain, Mouse liver; Cellular Location: Cytoplasm, Nucleus.

Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.

Specifications

• Antigen: TFIP11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TFIP11
• Gene Alias: 2810002G02Rik; AF097181; AW046167; bK445C9.6; hNtr1; HSPC006; NTR1; Septin and tuftelin-interacting protein 1; Spp382; Srr1; STIP; STIP-1; Tfip11; TIP33; TIP39; tuftelin interacting protein 11; tuftelin-interacting protein 11; tuftelin-interacting protein 33; tuftelin-interacting protein 39; tuftelin-interacting protein, 39 kD
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24144, 54723
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.31 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9ERA6, Q9UBB9
• Gene Symbols: TFIP11
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TFIP11 (NP_0362751).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov