Invitrogen™ TFPI Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116034

Catalog No. PIPA5116034

Description

Antibody detects endogenous levels of total TFPI.

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.

Specifications

• Antigen: TFPI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TFPI
• Gene Alias: A630013F22Rik; anti-convertin; AW552122; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; OTTHUMP00000163472; OTTHUMP00000205431; TFI; TFPI; TFPI1; Tissue factor pathway inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21788, 29436, 7035
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O54819, P10646, Q02445
• Gene Symbols: TFPI
• Immunogen: A synthesized peptide derived from human TFPI(Accession P10646), corresponding to amino acid residues R106-G156.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG