Invitrogen™ TFPI Polyclonal Antibody

Catalog No.	Quantity
PA143059	1 mg

Catalog No. PA143059 Supplier Invitrogen™ Supplier No. PA143059

Description

Sheep Polyclonal Antibody

PA1-43059 detects Tissue Factor Pathway Inhibitor in human samples. PA1-43059 has successfully been used in Western blot and ELISA applications. PA1-43059 was derived from human tissue factor pathway inhibitor.

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.

Specifications

• Antigen: TFPI
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 9.3 mg/mL
• Conjugate: Unconjugated
• Formulation: 50% water with 50% glycerol and no preservative
• Gene: TFPI
• Gene Accession No.: P10646
• Gene Alias: A630013F22Rik; anti-convertin; AW552122; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; OTTHUMP00000163472; OTTHUMP00000205431; TFI; TFPI; TFPI1; Tissue factor pathway inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
• Gene Symbols: TFPI
• Host Species: Sheep
• Immunogen: Human Tissue Factor Pathway Inhibitor.
• Purification Method: SDS-PAGE
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7035
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG