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Invitrogen™ TFPI Polyclonal Antibody
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Catalog No. PIPA588707
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100 μL
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PIPA588707 100 μL
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Catalog No. PIPA588707 Supplier Invitrogen™ Supplier No. PA588707
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DSEEDEEHTI ITDTELPPLK LMHSFCAFKA DDGPCKAIMK RFFFNIFTRQ CEEFIYGGCE GNQNRFESLE ECKKMCTRDN ANRIIKTTLQ QEKPDFCFLE EDPGICRGYI TRYFYNNQTK QCERFKYGGC LGNMNNFETL EECKNICEDG PNGFQVDNYG TQLNAVNNSL TPQSTKVPSL FVTKEGTNDG WKNAAH; Positive Samples: MCF-7, Mouse spleen, Rat lung; Cellular Location: GPI-anchor, Lipid-anchor, Microsome membrane.

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TFPI
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene TFPI
Gene Accession No. O54819, P10646, Q02445
Gene Alias A630013F22Rik; anti-convertin; AW552122; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; OTTHUMP00000163472; OTTHUMP00000205431; TFI; TFPI; TFPI1; Tissue factor pathway inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Gene Symbols TFPI
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 29-224 of human TFPI (NP_0010274521).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21788, 29436, 7035
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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