TFPI Recombinant Human Monoclonal Antibody (3A8), Invitrogen™

Human Recombinant Monoclonal Antibody

Supplier:  Thermo Scientific MA549984

Catalog No. FEMA549984

Description

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and μgtimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.

Specifications

• Antigen: TFPI
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
• Gene Accession No.: P10646, P19761
• Gene Symbols: TFPI
• Immunogen: Recombinant Human TFPI protein
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rabbit
• Form: Liquid

• Applications: ELISA, Neutralization
• Clone: 3A8
• Conjugate: Unconjugated
• Gene: TFPI
• Gene Alias: A630013F22Rik, anti-convertin, AW552122, EPI, Extrinsic pathway inhibitor, LACI, Lipoprotein-associated coagulation inhibitor, OTTHUMP00000163472, OTTHUMP00000205431, TFI, TFPI, TFPI1, Tissue factor pathway inhibitor, tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
• Host Species: Human
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100009401, 7035
• Content And Storage: -20°C or -80°C if preferred
• Isotype: IgG1