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TfR Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501567581
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50-156-7581 20 μL
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Catalog No. 50-156-7581 Supplier Bethyl Laboratories, Inc Supplier No. A304381AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Dog, Horse and Orangutan

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregcy, irritable bowel syndrome and in HIV patients.

Specifications

Antigen TfR
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene TFRC
Gene Accession No. P02786
Gene Alias CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1
Gene Symbols TFRC
Host Species Rabbit
Immunogen Between 125 and 175
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7037
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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