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  6. TfR (Transferrin R) Antibody (TFRC/1818) - Azide and BSA Free, Novus Biologicals™

TfR (Transferrin R) Antibody (TFRC/1818) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. p-7079130 Shop All R&D Systems Products
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NB254466100 100 μg
NB254466200 200 μg
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Catalog No. NB254466100 Supplier Novus Biologicals Supplier No. NBP254466100UG
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Description

Mouse Monoclonal Antibody

TfR (Transferrin R) Monoclonal specifically detects TfR (Transferrin R) in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.

Specifications

Antigen TfR (Transferrin R)
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone TFRC/1818
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, ELISA 2 - 4 ug/ml, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias CD71 antigen, CD71TRFR, p90, T9, TfR, TFR1, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr
Gene Symbols TFRC
Host Species Mouse
Immunogen Recombinant human extracellular TFRC protein fragment (aa94-212) (exact sequence is proprietary)
Purification Method Protein A or G purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Signal Transduction, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 7037
Test Specificity It recognizes a ∼90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Target Species Human
Content And Storage Store at -20 to -80C. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2b κ
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For Research Use Only

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