Invitrogen™ TFR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529137

Catalog No. PIPA529137

Description

Recommended positive controls: K562, HL-60. Predicted reactivity: Mouse (89%), Rat (88%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Specifications

• Antigen: TFR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tfr2
• Gene Alias: HFE3; MGC126368; TfR2; TFRC2; transferrin receptor 2; transferrin receptor protein 2; Trfr2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7036
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9UP52
• Gene Symbols: Tfr2
• Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human TFR2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG