Invitrogen™ TFR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542732

Catalog No. PIPA542732

Description

Peptide sequence: RAALSRQKLD HVWTDTHYVG LQFPDPAHPN TLHWVDEAGK VGEQLPLEDP Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Specifications

• Antigen: TFR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tfr2
• Gene Alias: HFE3; MGC126368; TfR2; TFRC2; transferrin receptor 2; transferrin receptor protein 2; Trfr2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7036
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9UP52
• Gene Symbols: Tfr2
• Immunogen: Synthetic peptide directed towards the N-terminal of human TFR2 (aa 180-229).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov