Invitrogen™ TFR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140257

Catalog No. PIPA5140257

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: SVLVVSEDVN YEPDLDFHQG RLYWSDLQAM FLQFLGEGRL EDTIRQTSLR ERVAGSAGMA ALTQDIRAAL SRQKLDHVWT DTHYVGLQFP DPAHPNTLHW VDEAGKVGEQ LPLEDPDVYC PYS.

This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Specifications

• Antigen: TFR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tfr2
• Gene Alias: HFE3; MGC126368; TfR2; TFRC2; transferrin receptor 2; transferrin receptor protein 2; Trfr2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7036
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UP52
• Gene Symbols: Tfr2
• Immunogen: Recombinant protein corresponding to Human TFR2. Recombinant protein control fragment (Product #RP-109320).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG