TG Monoclonal Antibody (OTI1F1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804409

Catalog No. 50-168-0233

Description

Thyroglobulin(Tg) is a glycoprotein homodimer produced predomitly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine.Thyroglobulinis secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Specifications

• Antigen: TG
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P01266
• Gene Symbols: TG
• Immunogen: Human recombit protein fragment corresponding to amino acids 20-358 of human TG produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1F1
• Conjugate: Unconjugated
• Gene: TG
• Gene Alias: AITD3, TGN
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7038
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid