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TG Mouse anti-Human, Clone: OTI8E4, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF804214

Catalog No. 50-166-6878


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Thyroglobulin (Tg) is a glycoprotein homodimer produced predomitly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
Specifications

Specifications

TG
Monoclonal
Unconjugated
TG
Lyophilized
TG
Human recombit protein fragment corresponding to amino acids 20-358 of human TG produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
OTI8E4
PBS with 8% trehalose and no preservative; pH 7.3
P01266
AITD3, TGN
Mouse
IgG2b
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
7038
SDS
Documents
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