TG Mouse anti-Human, Clone: UMAB270, lyophilized, UltraMAB™

Catalog No.	Quantity
50-168-5444	100 μg

Catalog No. 50-168-5444 Supplier OriGene Supplier No. UM800160CF

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Thyroglobulin(Tg) is a glycoprotein homodimer produced predomitly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine.Thyroglobulinis secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Specifications

• Antigen: TG
• Applications: Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: UMAB270
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: TG
• Gene Accession No.: P01266
• Gene Alias: AITD3, TGN
• Gene Symbols: TG
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 20-358 of human TG produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7038
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1