TGF-alpha Antibody (MF9), DyLight 755, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234683IR

Catalog No. NBP234683IR

Description

TGF-alpha Monoclonal specifically detects TGF-alpha in Human, Mouse, Rat, Bovine samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: TGF-alpha
• Classification: Monoclonal
• Conjugate: DyLight 755
• Gene Alias: protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
• Host Species: Mouse
• Molecular Weight of Antigen: 6 kDa
• Quantity: 0.1 mL
• Research Discipline: Angiogenesis, Cell Cycle and Replication, Signal Transduction
• Gene ID (Entrez): 7039
• Target Species: Human, Mouse, Rat, Bovine
• Form: Purified

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: MF9
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Symbols: TGFA
• Immunogen: A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGF-alpha (exact sequence is proprietary) (Uniprot: P01135)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only