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Invitrogen™ TGF alpha Monoclonal Antibody (1E8-G6)
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Catalog No. PIMA533316
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100 μg
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Catalog No. Quantity
PIMA533316 100 μg
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Catalog No. PIMA533316 Supplier Invitrogen™ Supplier No. MA533316
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Description

Mouse Monoclonal Antibody

1E8-G6 reacts with TGF-alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. 1E8-G6 is completely blocked by the peptide used for immunization. TGFalpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. In sections both cytoplasma and cell membranes are stained.

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TGF alpha
Applications Flow Cytometry, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 1E8-G6
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TGFA
Gene Accession No. P01135, P98138
Gene Alias EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF α; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFα; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1
Gene Symbols TGFA
Host Species Mouse
Immunogen Synthetic TGF-alpha 34-43 decapeptide linked carrier.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009482, 100034402, 7039
Target Species Human, Rabbit, Zebrafish
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgM κ
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