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TGF alpha Monoclonal Antibody (MF9), Invitrogen™

Catalog No. PIMA513907
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500 μL
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Catalog No. Quantity
PIMA513907 500 μL
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Catalog No. PIMA513907 Supplier Thermo Scientific Supplier No. MA513907

Description

Mouse Monoclonal Antibody

MA5-13907 targets Transforming Growth Factor alpha in WB applications and shows reactivity with Bovine, Human, mouse, and Rat samples. The MA5-13907 immunogen is a 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha.

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TGF alpha
Applications Western Blot
Classification Monoclonal
Clone MF9
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene TGFA
Gene Accession No. P01134, P01135, P48030
Gene Alias EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1
Gene Symbols TGFA
Host Species Mouse
Immunogen A 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21802, 24827, 540388, 7039
Target Species Bovine, Human, Mouse, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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