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Invitrogen™ TGF alpha Polyclonal Antibody
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Catalog No. PIPA5104226
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100 μL
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PIPA5104226 100 μL
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Catalog No. PIPA5104226 Supplier Invitrogen™ Supplier No. PA5104226
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TGF alpha.

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TGF alpha
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TGFA
Gene Accession No. P01134, P01135, P48030
Gene Alias EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF α; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFα; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1
Gene Symbols TGFA
Host Species Rabbit
Immunogen A synthesized peptide derived from human TGFA(Accession P01135), corresponding to amino acid residues V119-V160.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21802, 24827, 7039
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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