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TGF-alpha Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501733825 Shop All Proteintech Group Inc Products
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50-173-3825 150 μL
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Catalog No. 50-173-3825 Supplier Proteintech Group Inc Supplier No. 223081AP150UL
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Rabbit Polyclonal Antibody

Transforming growth factor (TGF) alpha is a 50-aa single-chain polypeptide derived from cleavage of transmembrane pro-TGF alpha. Sharing 42% identity with epidermal growth factor (EGF), TGF alpha binds the EGF receptor and activates downstream signaling pathways. TGF alpha is expressed by activated macrophages, keratinocytes, epithelial cells, and a variety of tumor-derived and transformed cell lines. This growth factor mediates cell proliferation and migration, as well as cellular transformation. Overexpression of TGF alpha has been linked to a variety of cancers, including the breast, colon, and stomach.

Specifications

Antigen TGF-alpha
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TGFA
Gene Accession No. P01135
Gene Alias EGF like TGF, ETGF, TFGA, TGF alpha, TGF type 1, TGFA
Gene Symbols TGFA
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7039
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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