TGF-beta Antibody (1D11.16.8) - BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 3 publications

Supplier:  Novus Biologicals NBP2451370.02MG

Catalog No. NBP24513700

Description

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin)

TGF-beta Monoclonal specifically detects TGF-beta in Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey samples. It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Sandwich ELISA, ELISA Capture (Matched Antibody Pair).

Specifications

• Antigen: TGF-beta
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Immunocytochemistry/Immunofluorescence 8-25 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0ug/ml, Sandwich ELISA, ELISA Capture (Matched Antibody Pair)
• Gene Accession No.: P10600, P61812
• Host Species: Mouse
• Molecular Weight of Antigen: 13 kDa
• Quantity: 0.02 mg
• Primary or Secondary: Primary
• Test Specificity: This MAb recognizes TGF beta 1, 2 and 3. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFbeta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), ELISA
• Clone: 1D11.16.8
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: TGFB1
• Immunogen: Bovine TGF-beta2 protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 7040
• Target Species: Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey
• Form: Purified

For Research Use Only