TGF-beta Antibody (1D11.16.8), DyLight 594, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP245137DL594

Catalog No. NB001414

Description

TGF-beta Monoclonal specifically detects TGF-beta in Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey samples. It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Sandwich ELISA.

Specifications

• Antigen: TGF-beta
• Classification: Monoclonal
• Conjugate: DyLight 594
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: TGFB1
• Immunogen: Bovine bone-derived TGF-beta 1 and TGF-beta 2
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This MAb recognizes TGF beta 1, 2 and 3. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFbeta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
• Content And Storage: Store at 4°C in the dark.

• Applications: Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), ELISA
• Clone: 1D11.16.8
• Dilution: Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Sandwich ELISA
• Gene Alias: CED, DPD1, LAP, TGFB, TGFB1, TGFbeta, transforming growth factor beta 1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Cytokine Research, Extracellular Matrix
• Gene ID (Entrez): 7040
• Target Species: Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey
• Isotype: IgG1 κ