TGFBR2 Monoclonal Antibody (OTI4F3), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-1894	100 μL

Catalog No. 50-168-1894 Supplier OriGene Supplier No. TA808048

Description

Mouse Monoclonal Antibody

The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Specifications

• Antigen: TGFBR2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI4F3
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: TGFBR2
• Gene Accession No.: P37173
• Gene Alias: AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII
• Gene Symbols: TGFBR2
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 23-294 of human TGFBR2 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7048
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1