TGFBR2 Polyclonal Antibody, Invitrogen™

Catalog No.	Quantity
PIPA588247	100 μL

Catalog No. PIPA588247 Supplier Thermo Scientific Supplier No. PA588247

Description

Rabbit Polyclonal Antibody

Immunogen sequence: HNTELLPIEL DTLVGKGRFA EVYKAKLKQN TSEQFETVAV KIFPYEEYAS WKTEKDIFSD INLKHENILQ FLTAEERKTE LGKQYWLITA FHAKGNLQEY LTRHVISWED LRKLGSSLAR GIAHLHSDHT PCGRPKMPIV HRDLKSSNIL VKNDLTCCLC DFGLSLRLDP TLSVDDLANS GQVGTARYMA PEVLESRMNL ENVESFKQTD VYSMALVLWE MTSRCNAVGE VKDYEPPFGS KVREHPCVES MKDNVLRDRG RPEIPSFWLN HQGIQMVCET LTECWDHDPE ARLTAQCVAE RFSELEHLDR LSG Positive Samples: HT-29, A-549, Mouse lung; Cellular Location: Cell membrane, Single-pass type I membrane protein

Transforming Growth Factor, beta receptor 2 (AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor Serine/Threonine kinases. It is involved in the regulation of cell proliferation. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). TGFBR2 encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. TGFBR2 also has a pseudogene on chromosome 14.

Specifications

• Antigen: TGFBR2
• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.44 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
• Gene: TGFBR2
• Gene Accession No.: P37173, P38438, Q62312
• Gene Alias: 1110020H15Rik, AAT3, AU042018, DNIIR, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, RIIDN, TAAD2, TbetaRII, TbetaR-II, TBR-II, tgf beta receptor 2, TGF-beta 2, TGF-beta receptor II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGFbeta RII, TGFbeta type II receptor, TGF-beta type II receptor, TGFbeta-RII, TGFBR2, Tgfbr2T, TGFR2, TGFR-2, transforming growth factor beta receptor 2, transforming growth factor beta receptor II, transforming growth factor beta receptor type II, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor 2, transforming growth factor, beta receptor II, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II alpha, transforming growth factor, beta receptor II beta, transforming growth factor, beta receptor II delta, transforming growth factor, beta receptor II epsilon, transforming growth factor, beta receptor II gamma, transforming growth factor, beta receptor IIT, transforming growth factor-b type II receptor, transforming growth factor-beta receptor type II, transforming growth factor-beta type II receptor
• Gene Symbols: TGFBR2
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 237-549 of human TGF beta Receptor II (TGFBR2) (NP_0032334)
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 21813, 7048, 81810
• Target Species: Human, Mouse, Rat
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG