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Invitrogen™ TGIF Polyclonal Antibody
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Catalog No. PIPA5102880
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100 μL
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PIPA5102880 100 μL
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Catalog No. PIPA5102880 Supplier Invitrogen™ Supplier No. PA5102880
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TGIF1.

TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TGIF
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TGIF1
Gene Accession No. P70284, Q15583
Gene Alias 5'-TG-3'-interacting factor 1; AA959811; AI462167; Homeobox protein TGIF1; HPE4; TALE family homeobox; TALE homeobox TG-interacting factor; Tfig; TG interacting factor 1; TGFB induced factor homeobox 1; TGFB-induced factor homeobox 1; TGIF; Tgif1; transforming growth factor-beta-induced factor
Gene Symbols TGIF1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TGIF1(Accession Q15583), corresponding to amino acid residues G324-Q374.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21815, 316742, 7050
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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