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Invitrogen™ TGIF Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA548328
Description
Predicted to react with chicken based on sequence homology.
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
Specifications
TGIF | |
Polyclonal | |
Unconjugated | |
TGIF1 | |
5'-TG-3'-interacting factor 1; AA959811; AI462167; Homeobox protein TGIF1; HPE4; TALE family homeobox; TALE homeobox TG-interacting factor; Tfig; TG interacting factor 1; TGFB induced factor homeobox 1; TGFB-induced factor homeobox 1; TGIF; Tgif1; transforming growth factor-beta-induced factor | |
Rabbit | |
Ammonium Sulfate Precipitation | |
RUO | |
21815, 7050 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
2.0 mg/mL | |
PBS with 0.09% sodium azide; pH 7.4 | |
P70284, Q15583 | |
TGIF1 | |
KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human TGIF1. | |
400 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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