TGIF1 Mouse anti-Human, Clone: OTI1A6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF802371

Catalog No. 50-166-5966

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.

Specifications

• Antigen: TGIF1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TGIF1
• Gene Alias: HPE4, TGIF
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7050
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1A6
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q15583
• Gene Symbols: TGIF1
• Immunogen: Full length human recombit protein of human TGIF1 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1