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TGIF1 Mouse anti-Human, Clone: OTI1A6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF802371

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.Specifications
TGIF1 | |
Monoclonal | |
Unconjugated | |
TGIF1 | |
HPE4, TGIF | |
Mouse | |
Affinity Chromatography | |
RUO | |
7050 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI1A6 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q15583 | |
TGIF1 | |
Full length human recombit protein of human TGIF1 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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