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TGIF1 Mouse anti-Human, Clone: OTI1H3, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF802287

Catalog No. 50-166-5932


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
Specifications

Specifications

TGIF1
Monoclonal
Unconjugated
TGIF1
Lyophilized
TGIF1
Full length human recombit protein of human TGIF1 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Western Blot
OTI1H3
PBS with 8% trehalose and no preservative; pH 7.3
Q15583
HPE4, TGIF
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
7050
SDS
Documents
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