Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Tocris Bioscience™ TH 1760

Click to view available options
Quantity:
10 mg
50 mg
Description
TH 1760 is a potent and selective NUDT15 (nudix hydrolase 15) inhibitor (IC50 = 29 nM). Displays selectivity for NUDT15 when assayed at 100 μM against other Nudix enzymes (MTH1, NUDT2, 5, 9, 12, 14, 18, 22) and pyrophosphatases or at 10 μM when assayed with a Eurofins Cerep Safety Screen44 panel. In vitro, TH 1760 treatment sensitizes cancer cell lines (NB4 and HL-60) to thiopurine.
Specifications
Specifications
Chemical Name or Material | 6-[[4-(1 H-Indol-5-ylcarbonyl)-1-piperazinyl]sulfonyl]-2(3 H)-benzoxazolone |
CAS | 2567914-01-4 |
Quantity | 50 mg |
Target | Hydrolase Inhibitors |
Molecular Formula | C20H18N4O5S |
Purity | 0.95 |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction