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  5. TH 588

TH 588

Catalog No. 533425
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent MTH1 inhibitor

TH 588 is a potent MTH1 inhibitor (IC50 = 5 nM). Induces oxidative DNA damage and reduces survival in cancer cells. Inhibits growth of breast and colorectal cancer xenografts in mice.

Specifications

Chemical Name or Material N4-Cyclopropyl-6-(2,3-dichlorophenyl)-2,4-pyrimidinediamine
CAS 1609960-31-7
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C13H12Cl2N4
Formula Weight Observed MW: 295.17
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