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Tocris Bioscience™ Thalidomide

Binds cereblon; also TNF-α synthesis inhibitor

Supplier:  Tocris Bioscience™ 0652/100

Catalog No. 06-521-00


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Description

Description

Thalidomide is a selective inhibitor of tumor necrosis factor α (TNF-α) synthesis. Anti-inflammatory; promotes T-cell activation. Predicted to reduce cytokine release in SARS-CoV-2 infection. Also binds cereblon, inhibiting ubiquitin ligase activity. Teratogenic and sedative-hypnotic. Promotes degradation of transcription factor SALL4.
Specifications

Specifications

99%
50-35-1
100 mg
M.W. (Observed): 258.23
N-(2,6-dioxo-3-piperidinyl)phthalimide
Room Temperature
Thalidomide
Thalidomide
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