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Tocris Bioscience™ Thalidomide Available on GSA/VA Contract for Federal Government customers only.

Binds cereblon; alsoTNF-α synthesis inhibitor

Manufacturer:  Tocris Bioscience™ 0652/100

Catalog No. 06-521-00

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Selective inhibitor of tumor necrosis factor α (TNF-α) synthesis. Anti-inflammatory; promotes T-cell activation. Predicted to reduce cytokine release in SARS-CoV-2 infection. Also binds cereblon, inhibiting ubiquitin ligase activity. Teratogenic and sedative-hypnotic. Promotes degradation of transcription factor SALL4.

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