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Invitrogen™ THAP1 Polyclonal Antibody
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Catalog No. PIPA577225
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100 μL
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Catalog No. Quantity
PIPA577225 100 μL
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Catalog No. PIPA577225 Supplier Invitrogen™ Supplier No. PA577225
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen THAP1
Applications Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Thap1
Gene Accession No. Q5U208, Q8CHW1, Q9NVV9
Gene Alias 4833431A01Rik; AW490810; DYT6; nuclear proapoptotic factor; THAP domain containing 1; THAP domain containing, apoptosis associated protein 1; THAP domain protein 1; THAP domain-containing apoptosis-associated protein 1; THAP domain-containing protein 1; THAP1
Gene Symbols Thap1
Host Species Rabbit
Immunogen Recombinant full length Human THAP1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 306547, 55145, 73754
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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