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THAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728085 Shop All Proteintech Group Inc Products
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50-172-8085 150 μL
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Catalog No. 50-172-8085 Supplier Proteintech Group Inc Supplier No. 125841AP150UL
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Description

Rabbit Polyclonal Antibody

12584-1-AP is a rabbit polyclonal antibody raised against full-length of human THAP1.

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5′-[AT]NTNN[GT]GGCA[AGT]-3′ core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.

Specifications

Antigen THAP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene THAP1
Gene Accession No. Q5U208, Q8CHW1, Q9NVV9
Gene Alias THAP1
Gene Symbols THAP1
Host Species Rabbit
Immunogen THAP1 Fusion Protein Ag3285
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 306547, 55145, 73754
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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