Thapsigargin, 95%, PROMO, Thermo Scientific Chemicals

Description

Applications

Thapsigargin- induces down regulation of the EGF receptor is independent of protein kinase C activation. It is also used as an inducer of stored Ca²⁺ release.

Solubility

Soluble in DMSO (20 mg/mL), ethanol (20 mg/mL), and acetone.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.

Specifications

Chemical Identifiers

• CAS: 67526-95-8
• Molecular Formula: C34H50O12
• Molecular Weight (g/mol): 650.76 g/mol
• MDL Number: MFCD00083511
• InChI Key: IXFPJGBNCFXKPI-FSIHEZPISA-N
• Synonym: thapsigargin, unii-z96bq26rzd, z96bq26rzd, chembl96926, octanoic acid 3s-3alpha, 3abeta, 4alpha, 6beta, 6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester, octanoic acid, 6-acetyloxy-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy azuleno 4,5-b furan-7-yl ester, 3s-3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha z ,9balpha, tg1, --thapsigargin, octanoic acid 3s-3alpha, 3abeta, 4alpha, 6beta,6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester, octanoic acid 3s-3alpha, 3abeta, 4alpha,6beta, 6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester
• PubChem CID: 126969181
• IUPAC Name: [(3S,3aR,4S,6S,6aS,7S,8S,9bR)-6-acetyloxy-4-butanoyloxy-3,3a-dihydroxy-3,6,9-trimethyl-8-(2-methylbut-2-enoyloxy)-2-oxo-4,5,6a,7,8,9b-hexahydroazuleno[4,5-b]furan-7-yl] octanoate
• SMILES: CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)C(\C)=C/C)C(C)=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(C)=O)[C@@H]12)OC(=O)CCC

• Color: White
• Quantity: 10 mg
• Sensitivity: Light Sensitive
• Merck Index: 14,9272
• Solubility Information: Soluble in DMSO, ethanol, and acetone.
• Percent Purity: 95%
• Physical Form: Film
• Chemical Name or Material: Thapsigargin

Safety and Handling

RTECSNumber	RH0325700
TSCA	No
Recommended Storage	Store at -20°C; Store under Nitrogen

RUO - Research Use Only