THEMIS Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A305277AT

Catalog No. 50-157-0003

Description

The recommended shelf life for this product is 1 year from date of receipt.

Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes. Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells. In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling. There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing.

Specifications

• Antigen: THEMIS
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q8N1K5
• Gene Symbols: THEMIS
• Immunogen: Between 591 and 641
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: THEMIS
• Gene Alias: THEMIS; thymocyte selection associated; C6orf190; C6orf207; FLJ40584; MGC163388; TSEPA; bA325O24.3; bA325O24.4; thymocyte selection pathway associated; thymocyte-expressed molecule involved in selection
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 387357
• Content And Storage: 4° C
• Form: Liquid