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THEMIS Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982145
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Catalog No. Quantity
50-198-2145 100 μL
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Catalog No. 50-198-2145 Supplier Bioss Supplier No. BS12329R
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Description

Rabbit Polyclonal Antibody

Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes. Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells. In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling. There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing.

Specifications

Antigen THEMIS
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Themis
Gene Accession No. Q8N1K5
Gene Alias bA325O24.3; bA325O24.4; C6orf190; C6orf207; E430004N04Rik; FLJ40584; Gasp; GRB2-associated protein; Grb2-associating protein; MGC163388; Protein THEMIS; Protein thylex; RGD1560849; signaling phosphoprotein specific for T cells; Spot; Themis; thylex; thymocyte expressed molecule involved in selection; thymocyte selection associated; thymocyte selection pathway associated; Thymocyte-expressed molecule involved in selection; TSEPA
Gene Symbols Themis
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human THEMIS.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 387357
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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