Human Cathepsin D, Recombinant Protein, Invitrogen™

Description

Recombinant Protein

Cathepsin D Recombinant Protein, RP-38944, from Invitrogen.

Cathepsin D is synthesized as a 54kDa precursor, which is proteolytically processed to an intermediate 48kDa single chain, which matures into more stable 34kDa and 14kDa two chain form. It is an astrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by diagesting the basement membrane, extracellular matrix, and connective tissue. Because of its mitogenic and proteolytic activities, it has been implicated as a prognostic marker in many tumor types. Cathespin D is expressed in epitthelial cells as well as in macrophages. This product is a recombinant protein corresponding to full-length human cathepsin D. On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa.

Specifications

• Accession Number: P07339
• Concentration: 0.1mg/mL
• For Use With (Application): Control
• Formulation: 0.05M tris HCl with 0.01M L-glutathione and no preservative; pH 7.5
• Gene ID (Entrez): 1509
• Name: Human Cathepsin D
• pH Range: 7.5
• Quantity: 10 μg
• Source: E. coli
• Storage Requirements: -20°C or -80°C if preferred
• Regulatory Status: RUO
• Common Name: Human Cathepsin D
• Gene Symbol: CTSD
• Specific Reactivity: Human
• Conjugate: Unconjugated
• Cross Reactivity: Hu
• Species: E. coli
• Recombinant: Recombinant
• Form: Liquid
• Protein Subtype: Recombinant
• Purity or Quality Grade: purified

in vitro research only.