Invitrogen™ Thermus thermophilus cas3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117525

Catalog No. PIPA5117525

Description

This antibody has been tested in direct-ELISA.

CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity. The N-terminal domain (residues 6-260) acts as a ssDNA endonuclease, has no activity on dsDNA.

Specifications

• Antigen: Thermus thermophilus cas3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ygcB
• Gene Alias: CRISPR-associated endonuclease; helicase Cas3
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3167883, 947229
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: Western Blot
• Concentration: 4.95 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: P38036, Q53VY2
• Gene Symbols: cas3, ygcB
• Immunogen: Recombinant Thermus thermophilus CRISPR-associated endonuclease/helicase Cas3 protein (120-226aa).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG