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Invitrogen™ Thimet Oligopeptidase Monoclonal Antibody (455710)
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Catalog No. PIMA524174
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100 μg
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Catalog No. Quantity
PIMA524174 100 μg
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Catalog No. PIMA524174 Supplier Invitrogen™ Supplier No. MA524174
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Description

Mouse Monoclonal Antibody

In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human Neurolysin is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thimet Oligopeptidase
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 455710
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Thop1
Gene Accession No. P52888
Gene Alias AI131655; AI327041; EC 3.4.24; EC 3.4.24.15; endo-oligopeptidase A; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; metalloendopeptidase; MP78; PZ-peptidase; soluble metallo-endopeptidase; Thimet oligopeptidase; thimet oligopeptidase 1; Thop1; TOP
Gene Symbols Thop1
Host Species Mouse
Immunogen E. coli-derived recombinant human Thimet Oligopeptidase/THOP1 Lys2-Cys689.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7064
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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