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Invitrogen™ Thimet Oligopeptidase Monoclonal Antibody (OTI2D3)
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Catalog No. PIMA525173
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100 μL
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PIMA525173 100 μL
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Catalog No. PIMA525173 Supplier Invitrogen™ Supplier No. MA525173
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Description

Mouse Monoclonal Antibody

Thimet Oligopeptidase Monoclonal Antibody for Western Blot, IHC (P)

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thimet Oligopeptidase
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2D3
Concentration 0.67 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Thop1
Gene Accession No. P52888
Gene Alias AI131655; AI327041; EC 3.4.24; EC 3.4.24.15; endo-oligopeptidase A; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; metalloendopeptidase; MP78; PZ-peptidase; soluble metallo-endopeptidase; Thimet oligopeptidase; thimet oligopeptidase 1; Thop1; TOP
Gene Symbols Thop1
Host Species Mouse
Immunogen Full length human recombinant protein of THOP1 produced in HEK293T cell.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7064
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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