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Invitrogen™ Thimet Oligopeptidase Polyclonal Antibody
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Catalog No. PIPA548031
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100 μg
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PIPA548031 100 μg
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Catalog No. PIPA548031 Supplier Invitrogen™ Supplier No. PA548031
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Description

Sheep Polyclonal Antibody

In Western blots, less than 5% cross-reactivity with recombinant human Neurolysin is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thimet Oligopeptidase
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Thop1
Gene Accession No. P52888
Gene Alias AI131655; AI327041; EC 3.4.24; EC 3.4.24.15; endo-oligopeptidase A; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; metalloendopeptidase; MP78; PZ-peptidase; soluble metallo-endopeptidase; Thimet oligopeptidase; thimet oligopeptidase 1; Thop1; TOP
Gene Symbols Thop1
Host Species Sheep
Immunogen E. coli-derived recombinant human Oligopeptidase/THOP1 Lys2-Cys689.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7064
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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