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Invitrogen™ Thimet Oligopeptidase Polyclonal Antibody
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Catalog No. PIPA583269
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100 μL
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PIPA583269 100 μL
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Catalog No. PIPA583269 Supplier Invitrogen™ Supplier No. PA583269
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AACAGDMADA ASPCSVVNDL RWDLSAQQIE ERTRELIEQT KRVYDQVGTQ EFEDVSYEST LKA Highest antigen sequence indentity to the following orthologs: Mouse - 78%, Rat - 76%.

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thimet Oligopeptidase
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Thop1
Gene Accession No. P52888
Gene Alias AI131655; AI327041; EC 3.4.24; EC 3.4.24.15; endo-oligopeptidase A; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; metalloendopeptidase; MP78; PZ-peptidase; soluble metallo-endopeptidase; Thimet oligopeptidase; thimet oligopeptidase 1; Thop1; TOP
Gene Symbols Thop1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human THOP1. Recombinant protein control fragment (Product #RP-104658).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7064
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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