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Invitrogen™ Thimet Oligopeptidase Polyclonal Antibody
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Catalog No. PIPA530229
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100 μL
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Catalog No. Quantity
PIPA530229 100 μL
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Catalog No. PIPA530229 Supplier Invitrogen™ Supplier No. PA530229
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa, HepG2, HCT116, mouse brain. Predicted reactivity: Mouse (92%), Rat (91%), Zebrafish (82%), Pig (94%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thimet Oligopeptidase
Applications Western Blot
Classification Polyclonal
Concentration 0.88 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Thop1
Gene Accession No. P52888, Q8C1A5
Gene Alias AI131655; AI327041; EC 3.4.24; EC 3.4.24.15; endo-oligopeptidase A; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; metalloendopeptidase; MP78; PZ-peptidase; soluble metallo-endopeptidase; Thimet oligopeptidase; thimet oligopeptidase 1; Thop1; TOP
Gene Symbols Thop1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Thimet Oligopeptidase. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50492, 7064
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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