Thioster-containing protein 1 Rabbit anti-Insect, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS0632R

Catalog No. 50-198-0405

Description

Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.

Specifications

• Antigen: Thioster-containing protein 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: p230; p240; p80 homolog; p80 telomerase homolog; rTLP1; telomerase associated protein 1; Telomerase protein 1; Telomerase protein component 1; Telomerase-associated protein 1; Tep1; TLP1; TP1; TROVE domain family, member 1; TROVE1; VAULT2
• Immunogen: KLH conjugated synthetic peptide derived from Anopheles stephensi Thioster-containing protein 1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: Antibody with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Insect
• Product Type: Antibody
• Isotype: IgG