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THOC7 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501569919
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50-156-9919 20 μL
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Catalog No. 50-156-9919 Supplier Bethyl Laboratories, Inc Supplier No. A305247AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with X. laevis, X. tropicalis and Bovine

Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5′ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi′s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.

Specifications

Antigen THOC7
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene THOC7
Gene Accession No. Q6I9Y2, Q7TMY4
Gene Alias NIF3L1BP1, fSAP24, NIF3L1-binding protein 1, Ngg1 interacting factor 3 like 1 binding protein 1, THO complex subunit 7 homolog, functional spliceosome-associated protein 24, hTREX30, ngg1-interacting factor 3-like protein 1-binding protein 1
Gene Symbols Thoc7
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 66231, 80145
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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