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Thrombomodulin Monoclonal Antibody (QBEND/40), Invitrogen™

Catalog No. PIMA516928
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PIMA516928 1 mL
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Catalog No. PIMA516928 Supplier Thermo Scientific Supplier No. MA516928

Description

Mouse Monoclonal Antibody

Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. A suggested positive control for immunohistochemical applications is lymph node. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL.

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thrombomodulin
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone QBEND/40
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation tissue culture supernatant diluted in 0.2M tris HCl with 5-10% FBS and 0.1% sodium azide; pH 7.4
Gene THBD
Gene Accession No. P07204
Gene Alias AHUS6; AI385582; BDCA3; BDCA-3; CD141; CD141 antigen; DC141; fetomodulin; sCD141; snoRNA MBII-339; soluble CD141; THBD; THPH12; THRM; thrombomdulin; thrombomodulin; thrombomodulin precursor; TM
Gene Symbols THBD
Host Species Mouse
Immunogen Human endothelium (thrombomodulin)
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100008887, 7056
Target Species Human, Rabbit
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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