Invitrogen™ Thrombospondin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597117

Catalog No. PIPA597117

Description

Immunogen sequence: HQDKDTTFDL FSISNINRKT IGAKQFRGPD PGVPAYRFVR FDYIPPVNAD DLSKITKIMR QKEGFFLTAQ LKQDGKSRGT LLALEGPGLS QRQFEIVSNG PADTLDLTYW IDGTRHVVSL EDVGLADSQW KNVTVQVAGE TYSLHVGCDL IDSFALDEPF YEHLQAEKSR MYVAKGSARE SHFRGLLQNV HLVFENSVED ILSKKGCQQG QGAEINAISE NTETLRLGPH VTTEYVGPSS ERRPEVCERS CEELGNMVQE L; Positive Samples: Mouse heart, Rat heart.

The Thrombospondin proteins (TSP 1-5) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell-surface proteins form complexes of both homo- and hetero-multimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1, and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin-binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.

Specifications

• Antigen: Thrombospondin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: THBS2
• Gene Alias: Thbs2; Thbs-2; thrombospondin 2; Thrombospondin2; thrombospondin-2; TSP2; TSP-2; TSP2thrombospondin-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21826, 292406
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.03 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q03350
• Gene Symbols: THBS2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human THBS2 (NP_0032382).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG