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Invitrogen™ Thyroglobulin Polyclonal Antibody
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Catalog No. PIPA582034
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100 μL
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Catalog No. Quantity
PIPA582034 100 μL
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Catalog No. PIPA582034 Supplier Invitrogen™ Supplier No. PA582034
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KMCSADYADL LQTFQVFILD ELTARGFCQI QVKTFGTLVS IPVCNNSSVQ VGCLTRERLG VNVTWKSRLE DIPVASLPDL HDIERALVGK DLLGRFTDLI QSGSFQLHLD SKTFPAETIR FLQGDHFGTS PRTWFGCSEG FYQVLTSEAS QDGLGCVKCP EGS Highest antigen sequence indentity to the following orthologs: Mouse - 76%, Rat - 76%.

The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thyroglobulin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TG
Gene Accession No. P01266
Gene Alias AITD3; cog; Colloid; congenital goiter; hereditary goitre; TG; Tgn; thyroglobulin; thyroglobulin precursor
Gene Symbols TG
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TG. Recombinant protein control fragment (Product #RP-100475).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7038
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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