TIA-1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A303990AT

Catalog No. 50-156-6616

Description

The recommended shelf life for this product is 1 year from date of receipt.

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Specifications

• Antigen: TIA-1
• Classification: Polyclonal
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: P31483, P52912
• Gene Symbols: TIA1
• Immunogen: Between 1 and 50
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: TIA1
• Gene Alias: TIA1; TIA1 cytotoxic granule-associated RNA binding protein ; TIA1 cytotoxic granule-associated RNA-binding protein; TIA1 protein; cytotoxic granule-associated RNA-binding protein; p40-TIA-1 (containing p15-TIA-1)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21841, 7072
• Content And Storage: 4° C
• Form: Liquid