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Invitrogen™ TIAF1 Polyclonal Antibody
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Catalog No. PIPA534538
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100 μg
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Catalog No. Quantity
PIPA534538 100 μg
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Catalog No. PIPA534538 Supplier Invitrogen™ Supplier No. PA534538
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Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-34538 can be used with blocking peptide PEP-1581.

TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection. Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation. TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIAF1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TIAF1
Gene Accession No. O95411
Gene Alias 12 kDa TGF-beta-1-induced antiapoptotic factor; MAJN; molecule associated with Jak-3 N-terminal; MYO18A; MYSPDZ; SPR210; TGFB1-induced anti-apoptotic factor 1; TGF-beta-1-induced antiapoptotic factor 1; TIAF; TIAF1
Gene Symbols TIAF1
Host Species Rabbit
Immunogen A 16 amino acid peptide near the amino terminus of human TIAF.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9220
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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