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Invitrogen™ TIAF1 Polyclonal Antibody
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Catalog No. PIPA562325
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100 μL
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Catalog No. Quantity
PIPA562325 100 μL
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Catalog No. PIPA562325 Supplier Invitrogen™ Supplier No. PA562325
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSSPSSPFRE QSFLCAAGDA GEESRVQVLK NEVRRGSPVL LGWVEQAYAD KCV Highest antigen sequence identity to the following orthologs: Mouse - 30%, Rat - 28%.

TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection. Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation. TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIAF1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TIAF1
Gene Accession No. O95411
Gene Alias 12 kDa TGF-beta-1-induced antiapoptotic factor; MAJN; molecule associated with Jak-3 N-terminal; MYO18A; MYSPDZ; SPR210; TGFB1-induced anti-apoptotic factor 1; TGF-beta-1-induced antiapoptotic factor 1; TIAF; TIAF1
Gene Symbols TIAF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TIAF1. Recombinant protein control fragment (Product #RP-100356).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9220
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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